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4 associated genes
16 signs/symptoms

PROTEIN INTERACTIONS: 1

Bartsocas-Papas syndrome

1 OMIM reference -
1 associated gene
28 signs/symptoms

MALT lymphoma

Bartsocas-Papas syndrome

BIRC3	(UniProt - OMIM)		RIPK4	(UniProt - OMIM)
FOXP1	(UniProt - OMIM)
IGH	(UniProt)
MALT1	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	BIRC3	(0.75)	RIPK4

Citations in the biomedical literature:

MALT lymphoma		Bartsocas-Papas syndrome
	Synonym(s): - Extranodal marginal zone B-cell lymphoma - MALToma - Mucosa-associated lymphatic tissue lymphoma - Mucosa-associated lymphoid tissue lymphoma		Synonym(s): - Autosomal recessive popliteal pterygium syndrome - Lethal popliteal pterygium syndrome

	Classification (Orphanet): - Rare hematologic disease - Rare oncologic disease		Classification (Orphanet): - Rare developmental defect during embryogenesis - Rare genetic disease - Rare maxillo-facial surgical disease - Rare otorhinolaryngologic disease - Rare skin disease

	Classification (ICD10): - Neoplasms -		Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -

	Epidemiological data: Class of prevalence: 1-9 / 100 000 Average age onset: adulthood Average age of death: normal Type of inheritance: multigenic/multifactorial		Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: neonatal/infancy Average age of death: before age 5 Type of inheritance: autosomal recessive

	External references: No OMIM references No MeSH references		External references: 1 OMIM reference - No MeSH references

MALT lymphoma		Bartsocas-Papas syndrome
	Very frequent - Asthenia / fatigue / weakness - Epigastralgia / heartburn / gastric / duodenal ulcer / gastritis - Fever / chilling - Hematologic / blood / lymphatic cancer - Hyperhidrosis / increased sweating - Lung / pulmonary infiltrates - Nausea / vomiting / regurgitation / merycism / hyperemesis - Weight loss / loss of appetite / break in weight curve / general health alteration Frequent - Constipation Occasional - Acute abdominal pain / colic - Chronic uveitis / blepharitis / episcleritis / scleritis / conjonctivitis / keratitis - Defect / anomaly of lacrimal system - Lymphadenopathy / polyadenopathies - Mediastinal / hilar adenopathies - Repeat respiratory infections - Thyroid anomalies		Very frequent - Absent / decreased lashes - Absent / decreased / thin eyebrows - Autosomal recessive inheritance - Cleft lip and palate - Cryptophthalmia / ankyloblepharon / synblepharon - Distal phalangeal bones of toes hypoplasia / absence - Early death / lethality - Hypotrichosis / atrichia / atrichiasis / scalp hairlessness - Limited opening of the mouth - Median cleft lip - Microcephaly - Popliteal web - Structural anomalies of the genital system - Syndactyly of fingers / interdigital palm - Syndactyly of toes - Synostosis - Talipes-varus / metatarsal varus - Thin / hypoplastic toenails Frequent - Coloboma of the eyelid - Corneal clouding / opacity / vascularisation - Intellectual deficit / mental / psychomotor retardation / learning disability - Micrognathia / retrognathia / micrognathism / retrognathism - Microstomia / little mouth - Short / small nose - Thin / hypoplastic ala nasi - Thumb hypoplasia / aplasia / absence Occasional - Agenesis / hypoplasia / aplasia of kidneys - Congenital cardiac anomaly / malformation / cardiopathy